ORIGINAL ARTICLE |
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Bioactive compounds are a rich source of preventive substances for many diseases. In the present study was attempt to evaluate the in silico docking studies of calendoflavobioside of Calendula officinalis Linn. on wound healing. The compound calendoflavobioside were screened for the wound healing biomarker matrix metallo proteinases 8 and 12 by molecular docking. The result of the study indicates that calendoflavobioside has good affinity with MMP 8(-3.00kcal/mol) and MMP 12(-3.08kcal/mol).
Key words: Metallo Proteinase 8, Metallo Proteinase 12, Calendula officinalis, Calendoflavobioside, Molecular docking