TY - JOUR AU - Shobana, Gunasekaran AU - Nayagam, Agnel Arul John T1 - In silico Docking Studies of Calendoflavobioside of Calendula officinalis Linn. against Matrix Metallo Proteinase 8 and 12 on Wound Healing JO - Journal of Stress Physiology & Biochemistry Y1 - 2025/august VL - 21 IS - 3 SP - 128 EP - 135 UR - http://www.jspb.ru/issues/2025/N3/JSPB_2025_3_128-135.pdf KW - Metallo Proteinase 8 KW - Metallo Proteinase 12 KW - Calendula officinalis KW - Calendoflavobioside KW - Molecular docking U1 - 1997-0838 N2 - Bioactive compounds are a rich source of preventive substances for many diseases. In the present study was attempt to evaluate the in silico docking studies of calendoflavobioside of Calendula officinalis Linn. on wound healing. The compound calendoflavobioside were screened for the wound healing biomarker matrix metallo proteinases 8 and 12 by molecular docking. The result of the study indicates that calendoflavobioside has good affinity with MMP 8 (-3.00kcal/mol) and MMP 12 (-3.08kcal/mol). ER -