TY  - JOUR
AU  - Kolhekar, M. B.
AU  - Ghodeshwar, P. L.
AU  - Rahate, U. S.
AU  - Dhurvey, V. T.
T1  - Effect of Glyphosate on Intestine in Fish: a Review
JO  - Journal of Stress Physiology & Biochemistry
Y1  - 2026/june
VL  - 22
IS  - 2
SP  - 28
EP  - 35
UR  - http://www.jspb.ru/issues/2026/N2/JSPB_2026_2_28-35.pdf
KW  - Glyphosate
KW  - Clarias gariepinus
KW  - intestine
KW  - oxidative stress
KW  - gut microbiota
KW  - ecotoxicology
U1  - 1997-0838
N2  - Globally glyphosate is the most widely used broad-spectrum herbicide due to its efficacy and low cost but, with such wide spread use on crops it has contaminated our freshwater systems and represents a substantial threat to aquatic life due to adverse glyphosate exposure. Fish are very susceptible to glyphosate exposure through agricultural runoff into water bodies as well as from contaminated water. It’s worth noting, that bony fish, such as Clarias gariepinus, have shown great susceptibility to glyphosate exposure. The gastrointestinal tract, being involved in digestion/microbiota- host interactions, nutrient absorption, and immune function, is of special concern regarding glyphosate-induced effects in fish. Numerous studies have shown that glyphosate produces histopathological changes, oxidative stress, digestive enzyme inhibition, and microbiota dysbiosis under aerobic and anaerobic conditions, in fish and other vertebrates. The purpose of this review is to examine the impact of glyphosate on bony fish (teleosts) gut health, emphasising histopathological damage, enzyme disruption, oxidative stress mechanisms, and microbiota alteration(s). These data will be invaluable for assessing ecological risks and promote sustainability within aquaculture practices.
ER  -