TY  - JOUR
AU  - Hashim, K. A.
AU  - Badusha, M.
T1  - Influence of Benzene Hexachloride (Hexachlorocyclohexane) on Certain Endocrine Glands of South Indian Gerbil, Tatera indica cuvieri
JO  - Journal of Stress Physiology & Biochemistry
Y1  - 2026/march
VL  - 22
IS  - 1
SP  - 99
EP  - 109
UR  - http://www.jspb.ru/issues/2026/N1/JSPB_2026_1_99-109.pdf
KW  - BHC
KW  - hexachlorocyclohexane
KW  - endocrine glands
KW  - gerbil
KW  - histopathology
KW  - pesticide toxicity
U1  - 1997-0838
N2  - The present study investigates the histopathological effects of Benzene Hexachloride (BHC/Hexachlorocyclohexane) on selected endocrine glands of the South Indian gerbil, Tatera indica cuvieri. Fifteen adult male gerbils were divided into three groups: normal, control, and experimental. Experimental animals were administered BHC orally mixed with tapioca powder at a dose of 250 mg/kg body weight. Pituitary, thyroid, adrenal, and pancreas were examined histologically after 7 and 14 days using Haematoxylin–Eosin staining. Distinct degenerative changes were observed in pituitary, thyroid, and adrenal glands of BHC-treated animals, while the pancreas remained largely unaffected. Behavioral dullness and a reduction in body weight accompanied histological degeneration. This study demonstrates that BHC exerts toxic effects predominantly on the endocrine system of gerbils, except the pancreas
ER  -