Journal of Stress Physiology & Biochemistry, Vol. 18 No. 4 2022, pp. 34-40 ISSN 1997-0838
Original Text Copyright (cc) 2022 by   K. Shakila

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Assessment of HRBC membrane stabilizing activity from flavonoids of Asystasia gangetica

K. Shakila

1 Assistant Professor of Chemistry, Arignar Anna Government Arts and Science College, Karaikal, Pondicherry, India.


Received May 25, 2022

Flavonoids from the largest single-family of naturally occurring oxygen-containing heterocyclic compounds. Benzo pyrone of various levels of saturation, oxidation, and substitution constitutes the basic skeleton for these polyphenolics. Asystasia gangetica belongs to the family Acanthaceae and has been investigated for flavonoids The white flowers of Asystasia gangetica on suitable extraction and fractionation have afforded a rare flavone glycoside viz. luteolin 7 – O – rutinoside and a flavonol glycoside viz. patuletin 3 – O- glucuronide the structure of which has been established by methods like 1H NMR, 13C NMR, UV, PC, chemical reactions, and hydrolytic studies. A biphasic activity has been observed in the HRBC membrane stabilization, an in vitro investigation against hypotonicity induced haemolysis of the isolated flavonoids.

Key words:    Patuletin, Luteolin, Asystasia gangetica, Acanthaceae family

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