ORIGINAL ARTICLE

Assessment of HRBC membrane stabilizing activity from flavonoids of Asystasia gangetica

Flavonoids from the largest single-family of naturally occurring oxygen-containing heterocyclic compounds. Benzo pyrone of various levels of saturation, oxidation, and substitution constitutes the basic skeleton for these polyphenolics. Asystasia gangetica belongs to the family Acanthaceae and has been investigated for flavonoids The white flowers of Asystasia gangetica on suitable extraction and fractionation have afforded a rare flavone glycoside viz. luteolin 7 – O – rutinoside and a flavonol glycoside viz. patuletin 3 – O- glucuronide the structure of which has been established by methods like ¹H NMR, ¹³C NMR, UV, PC, chemical reactions, and hydrolytic studies. A biphasic activity has been observed in the HRBC membrane stabilization, an in vitro investigation against hypotonicity induced haemolysis of the isolated flavonoids.