The paper presents some natural supramolecular sanogenetic mechanisms that occur in the body of chickens after dermanyssosis with the participation of stress-associated hormones, cortisol and triiodothyronine, during desacarisation. This study contains a description of physiological and biochemical bases of recovery of the body after an extreme environmental factor (haematophagous ectoparasite Dermanyssus gallinae). Particular scientific interest is in studying changes in the dynamics of morphophysiological and biophysiochemical blood parameters in birds with eliminated stress factor of extreme strength, an aggressive haematophagous ectoparasite, and a concurrent desacarisation of the poultry building with a synthetic pyrethroid-based drug. At the same time, partially normalized key parameters of endocrine and metabolic homeostasis was detected in the birds after dermanyssosis, which occurred due to activated natural sanogenetic mechanisms, and compensatory and adaptive reactions. Significant changes were detected in the hormonal state in the chickens from the experimental group that resulted in the decreased cortisol-producing function of the adrenal glands and the increased thyroid gland functional activity. The latter is, in our opinion, the most important sanogenetic mechanism that ensures maintenance of the antioxidant status, which is especially necessary when the body recovers after an extreme environmental factor. Along with this, a natural recovery of the RBC elements as well as immunity was observed. At the same time, decreased intensity of lipid peroxidation processes in the experimental chickens predetermines maintaining the integrity of these cells.
Key words: dermanyssosis, desacarisation, sanogenesis, sanogenetic mechanisms, stress factor