The present study was planned with a view to assess the efficacy of Punarnava Mandura in Pandu roga on the basis of hematological parameters. Hematological parameters are one of the best tools to accessed anemia in individuals. Mandura Bhasma which is one of the good Haemetinic proved by various research works (experimental and clinical) is main ingredient of this formulation. Punarnava Mandura is a very well known drug by its “Raktajanya” property mentioned by Acharya Charaka.. On the basis of this, the reference regarding this in “Bhaishajya Ratnavali” was assessed for the preparation of this formulation used for management of Pandu clinically. Pandu roga is a disease characterized by pallor of body which strikingly resembles with ‘Anaemia’ of Modern science, disease referring to reduction in number of RBCs per cumm of blood and quantity of Hb resulting in pallor like other symptoms. Pandu Roga can be effectively compared with Anemia on the grounds of its similar signs and symptoms in the modern medicine, there is good treatment for Anemia with considerable result but that is only for acute deficiency Anemias, no significant therapy is there for chronic Anemia which occurs due to metabolic defects. So Ayurveda can provide better management. The world’s population is increasing at a rapid rate, with the result most of the people are living in un-hygienic, under-nourishing conditions and facing various effects of stress and strain factor. Illiteracy is also a problem in developing countries like India due to which great majority of people are living under poverty line, who cannot get quantitatively sufficient diet. Even pregnant ladies do not get proper nourishment due to which mother and infant mortality is at higher level.
Key words: Hematological parameters, pandu roga, punarnava mandur