TY - JOUR AU - Kumar, G. Nirmal AU - Maran, Madhu Priya AU - Shankar, S. Ravi T1 - Mineral composition, Antioxidant and Anti-inflammatory Activities of the Crude Extract of Leaves of Carica papaya L. JO - Journal of Stress Physiology & Biochemistry Y1 - 2021/march VL - 17 IS - 1 SP - 13 EP - 23 UR - http://www.jspb.ru/issues/2021/N1/JSPB_2021_1_13-23.pdf KW - Carica papaya L. KW - antioxidant KW - anti inflammatory KW - mineral composition U1 - 1997-0838 N2 - Carica papaya L. (family Caricaceae) commonly known as papaya is a well-known fruit crop also having under-utilized medicinal potential. Mineral analysis shows that a significant level of potassium (207.10±0.40 mg/100g) and phosphorous (65.60±0.59 mg/100g) are present. Antioxidant activity of hexane, chloroform, ethyl acetate and ethanol crude leaf extracts were evaluated. IC50 hexane fraction (321.82±0.78) demonstrated the highest ABTS radical scavenging activity and IC50 of the chloroform fraction (623.23±1.32) showed the strongest DPPH free radical scavenging activity and their activities were stronger than that of ascorbic acid. Ethanolic extract IC50 shows significant anti-inflammatory activity (173.66±1.24) when compared with other extract fractions. The present study signifies that the leaves of C. papaya are rich in minerals and known to possess significant antioxidant and anti-inflammatory activities. This shall be further explored to identify novel bioactive substances with pharmaceutical applications. ER -