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Background and objectives: Diabetes
mellitus is the most common endocrine disorder and the leading cause of
death and disability in the world. Magnesium is the most common
intracellular cation involved in insulin mediated glucose uptake. This
study was conducted in type 2 diabetic patients to assess fasting blood
glucose (FBS), HbA1c and serum magnesium levels and compare it with
normal controls.
Materials and Methods: This was
a case control study which included 50 patients with type 2 diabetes
mellitus and 50 healthy controls. Serum magnesium was estimated by
calmagite endpoint method. HbA1c was estimated by immunoturbidimetry
method. Statistical analysis was done using SPSS.
Results and discussion:
Decrease in mean level of serum magnesium were observed among diabetic
patients. A negative correlation was observed between serum magnesium
and HbA1c. A linear regression analysis showed an inverse relationship
between serum magnesium and glycemic control among patients with
diabetes mellitus.
Conclusion: We concluded that
type 2 diabetic patients who are at risk of developing microvascular
complications with poor glycemic control must be regularly monitored
for serum magnesium levels.
