TY - JOUR AU - Martusevich, Andrew K. AU - Soloveva, Anna G. AU - Krasnova, Svetlana Yu. AU - Galka, Alexander G. AU - Golygina, Elena S. T1 - Assessment of the Action of Сold Helium Plasma on Metabolic and Physico-chemical Parameters of Rats Blood JO - Journal of Stress Physiology & Biochemistry Y1 - 2019 VL - 15 IS - 1 SP - 25 EP - 31 UR - http://www.jspb.ru/issues/2019/N1/JSPB_2019_1_25-31.pdf KW - helium cold plasma KW - stress KW - blood plasma KW - oxidative metabolism KW - crystallization U1 - 1997-0838 N2 - The aim of this paper was to study the effect of cold helium plasma on the parameters of oxidative metabolism and crystallogenic activity of rat blood plasma. Material and methods: The experiment was performed on 20 male Wistar rats divided into control (n=10, without manipulation) and main (n=10) groups. Animals of the main group underwent a course, which included 10 daily procedures for processing a pre-epilated area of the back skin (area – 10% of the body surface) with a stream of helium cold plasma (duration – 1 min.). Upon completion of the course, the intensity of lipid peroxidation, total antioxidant activity, malon dialdehyde level and superoxide dismutase activity were determined in the blood of all rats, and crystallogenic properties were evaluated. The conjugation of potential shifts was carried out by correlation analysis. Results: It was found that cold helium plasma transforms oxidative metabolism of blood plasma and its crystallogenic properties, acting as an agent with moderate antioxidant properties and a stimulant of dehydration structuring. In this case, the antioxidant effect is realized, among other things, due to the activation of superoxide dismutase. ER -