Culturable Actinobacteria Associated with Baikal Algae: Diversity and Antimicrobial Activity

Axenov-Gribanov, D.V.; Kostka, D.V.; Protasov, E.S.; Emshanova, V.A.; Vereshchagina, K.P.; Krasnova, M.E.; Gorbenko, I.V.; Lubyaga, Y.A.; Voycehovskaya, I.V.; Timofeyev, M.A.

Journal of Stress Physiology & Biochemistry, Vol. 14 No. 2 2018, pp. 19-25 ISSN 1997-0838
Original Text Copyright (cc) 2018 by Axenov-Gribanov, Kostka, Protasov, Emshanova, Vereshchagina, Krasnova, Gorbenko, Lubyaga, Voycehovskaya, and Timofeyev

ORIGINAL ARTICLE

Culturable Actinobacteria Associated with Baikal Algae: Diversity and Antimicrobial Activity

Axenov-Gribanov D.V.^1,2*, Kostka D.V.¹, Protasov E.S.^1,2, Emshanova V.A.¹, Vereshchagina K.P.^1,2, Krasnova M.E.¹, Gorbenko I.V.¹, Lubyaga Y.A.^1,2, Voycehovskaya I.V.¹, Timofeyev M.A.¹

¹ Institute of Biology at Irkutsk State University, Irkutsk, 3 Lenin str., Russia
² Baikal Research Centre, Irkutsk, 21 Lenin str., Russia

*E-Mail: denis.axengri@gmail.com

Received June 10, 2018

The aim of the study was to assess the biodiversity of culturable strains of actinobacteria isolated from freshwater Baikal algae Draparnaldioides baicalensis and to assess the antimicrobial activity of compounds against Gram-positive bacteria. In the course of this study, we isolated both widespread strains of the genus Streptomyces, and rare representatives of the genus Saccharopolyspora, Nonomuraea, Rhodococcus and Micromonospora. We demonstrated that the strains produce natural products with antimicrobial activity. Considering the large number of rare and active strains associated with the endemic algae D. baicalensis, we shown that these microorganisms have a value for biomedical and biotechnological development and to discovery of new natural compounds, including antibiotics.

Key words: Baikal, algae, endemics, natural products, antimicrobial activity, B. subtilis