Journal of Stress Physiology & Biochemistry, Vol. 12 No. 3  2016, pp. 12-17 ISSN 1997-0838
Original Text Copyright (cc) 2016 by  Martusevich, Martusevich and Kovaleva



ORIGINAL ARTICLE
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QueryDate : 2016-12-24
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Biocrystallomics Methods in Estimation of the Action of Different Stress Factors

A.K. Martusevich1, A.A. Martusevich2, L.K. Kovaleva3

1 Department of experimental medicine, Privolzhsky Federal Medical Research Centre; 603155, Nizhny Novgorod, Verhnevolzhskaya nab., 18/1, Russia.
2 Department of biochemistry and physiology, National Research Nizhny Novgorod State University named after N.I. Lobachevskiy; 603000, Nizhny Novgorod, Gagarin av., 23, Russia.
3 Laboratory of biocrystallomics and free radical medicine, Kirov State Medical University; 610027, Kirov, Karl Marx st., 112, Russia

*E-Mail: cryst-mart@yandex.ru

Received May 24, 2016

Background: it is well-known that in critical conditions the general response on stimulation is common adaptation syndrome, which includes the mobilization of organism reserves and restructuring of homeostatic mechanisms. However, the action of particular agents has some specific features even under the universal adaptive response. This determines relevant features of the response of the organism, which transform the manifestation of the adaptation syndrome.
Aim:
The aim of this investigation is study of action of short-term physical load and epinephrine administration on crystallogenic properties of rats’ blood serum.
Results:
it is stated that swimming and epinephrine administration causes increasing of crystallogenic activity of rats’ blood serum. This trend is more pronounced for the first impact. In addition, both factors increase the degree of destruction of elements of the sample. Maximal elevation of facia destruction degree was fixed for the administration of epinephrine.
Conclusion:
we show the uniformity of response of the organism to stress stimuli of different etiology, which is manifested in the development of typical pathological processes implemented by a single algorithm regardless of the primary initiating agent.

Key words:    biocrystallomics, stress factors, blood serum

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