QueryDate : 2016-12-24
Cites : 7
| ORIGINAL
ARTICLE |
| | | Data source : Google Scholar QueryDate : 2016-12-24 Cites : 7 |
There
is growing evidence that oxidative stress contributes to the
pathogenesis of anxiety disorders. Our aim was to measure oxidative
stress in anxiety disorders subjects, and assesses the potential
confounding influences of anti anxiety therapy. Serum malondialdehyde
and antioxidant levels were estimated in patients at the time of
presentation and also after anti- anxiety therapy for 3 months. During
the period of study no antioxidant/s was given to the patients and
control subjects. Serum malondialdehyde levels were significantly
higher in the anxiety disorders patients in comparison to control
cases. Also, the antioxidant activity of enzymes super oxide dismutase,
glutathione and non enzymatic antioxidant levels of vitamins E and C
were significantly lower in patients compared to controls at the
initial presentation. After 3 months of anti anxiety treatment all the
above parameters showed reversal in the respective levels of serum
malondialdehyde and antioxidant activity. Anti anxiety medications
results in reduced oxidative stress which indicates that oxidative
stress is not the cause, but rather a consequence, of anxiety disorders.
