Journal of Stress Physiology & Biochemistry, Vol. 6 No. 2
2010, pp. 19-25 ISSN 1997-0838
Original Text Copyright (cc) 2010 by Kataria, Kataria, Maan and Gahlot
ORIGINAL
ARTICLE
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QueryDate : 2016-12-24
Cites : 31
Evaluation of oxidative stress in brucella infected cows
N. Kataria 1*, A.K Kataria 2, R. Maan 1,
A.K.Gahlot 3
1 Department of Veterinary
physiology, College of Veterinary and Animal Science, S K Rajasthan
Agriculture University, Bikaner – 334 001, Rajasthan, India 2 Apex Centre for Animal Disease Investigation, Monitoring
and Surveillance, College of Veterinary and Animal Science, S K
Rajasthan Agriculture University, Bikaner – 334 001, Rajasthan,
India 3 Department of Veterinary Medicine, College of Veterinary
and Animal Science, S K Rajasthan Agriculture University, Bikaner – 334
001, Rajasthan, India Phone: 0091 – 151 - 2546399 *Email- nalinikataria@rediffmail.com
Received March 6, 2010
Oxidative stress can influence the metabolism of
cells in vital organs of the body. Oxidative stress is extremely
dangerous as it does not exhibit any symptom and is recognisable with
great difficulty by means of laboratory methods. It can be monitored
with several biomarkers like antioxidants and pro-oxidants which can be
assessed in serum. The inexorableness of exposure of cows to brucella
infection makes oxidative stress associated with this infection an
appropriate field of investigation. There is paucity of work to detect
stress, which is essential to take timely corrective measures and to
save the animal population. Therefore the investigation was carried out
to evaluate oxidative stress in the cows suffering from brucellosis.
For this serum biomarkers of oxidative stress viz. vitamin C, vitamin
E, catalase, monoamine oxidase, glutathione reductase, superoxide
dismutase, glutathione, xanthine oxidase, oxidase and peroxidase were
determined. Results indicated that vitamin C, vitamin E and glutathione
activity decreased significantly in affected cows as compared to
healthy cows. Serum catalase, superoxide dismutase, monoamine oxidase,
glutathione reductase, xanthine oxidase, oxidase and peroxidase
activities increased significantly in affected cows as compared to
healthy cows. Decreased activity of vitamin C, vitamin E and
glutathione indicated towards their depletion which generally occurs in
the oxidative stress to scavenge the free radicals. It was concluded
that oxidative stress was there in the animals. This study recommends
the use of antioxidants in affected cows.
