Journal of Stress Physiology & Biochemistry, Vol. 6 No. 2 2010, pp. 4-9 ISSN 1997-0838
Original Text Copyright (cc) 2010 by Koshoridze, Menabde, Kuchukashvili, Chachua and Chipashvili



ORIGINAL ARTICLE
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Quantitative Alterations in the Products of Lipid Peroxidation under Stress

N.I. Koshoridze, K.O. Menabde, Z.T. Kuchukashvili, M.V.Chachua, M.D. Chipashvili

Faculty of Exact and Natural Sciences, Iv. Javakhishvili Tbilisi State University. Georgia, 0128, Tbilisi, University St. 13
E-mail: ketimenabde@yahoo.com Tel.: + 995 32 303 997 (Menabde K.) E-mail: tebr50@yahoo.com (Chachua M.)

Received February 25, 2010

Development of changes in the content of nitrogen oxide (NO) in the mitochondrial and cytosolic fractions of the brain and cardiomyocytes as well as in the blood plasma of white rats under the conditions of isolation of the animals and disturbances in their circadian cycles were studied. It was found out that the amount of NO under stress changes in various ways. Simultaneously, the quantitative changes in concentration of general lipids and intensity of peroxidation were also revealed.

key words: nitrogen oxide, lipids, malonic dialdehyde, peroxidation



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