Faculty of Exact and Natural
Sciences, Iv. Javakhishvili Tbilisi State University. Georgia, 0128,
Tbilisi, Chavchavadze Tel.: (995 32) 34 80 48 (N. Koshoridze) E-mail: tebr50@yahoo.com (M. Chachua)
Received February 26, 2009
The development of changes in the activity of creatinkinase,
aldolase and succinatdehydrogenase in brain cells under 30-day long
stress induced by isolation and violated diurnal cycle has been
studied. It was shown that these enzymes heterogeneously responded to
30-day long stress. Particular sensitivity was recorded in the case of
succinatedehydrogenase, which showed the decline of activity in various
sections of the brain by 60-80% on average. Unlike
succinatedehydrogenase, aldolase activity increased on the 10th day of
stress and then declined. Similar results were observed in relation to
phosphokinase activity.
